![]() For these reasons, it is necessary to establish a standardized ICG angiography protocol and develop a quantitative analysis protocol for the objective assessment. ![]() Additionally, ICG angiography evaluations have mostly relied on surgeons’ subjective judgment. Most previous studies have been small-scale single-center studies, and there is no standardized ICG angiography protocol to date. Recently, two multicenter randomized clinical trials reported that ICG angiography did not significantly reduce the incidence of anastomotic leakage. Many studies have demonstrated the clinical utility of ICG angiography for reducing anastomotic complications. ICG angiography can unequivocally reveal unfavorable perfusion zones and provide quantitative parameters to predict the risk of hypoperfusion-related anastomotic complications. In this review, we discuss the clinical utility and the standardization of ICG angiography. However, there is debate on its contribution to reducing anastomotic complications. The use of ICG angiography is rapidly spreading in the field of colorectal surgery. ![]() Indocyanine green (ICG) angiography is a simple noninvasive perfusion assessment modality. The intestinal perfusion status at the anastomotic site is an important modifiable risk factor, and surgeons should carefully evaluate and optimize the perfusion at the intended site of anastomosis. Abstract Anastomotic complications occur after 5% to 20% of operations for rectosigmoid colon cancer.
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